Introduction Functional constipation (FC) is a common digestive system disease, with an uptrend in morbidity and mortality, resulting in huge social and economic losses.Although the guidelines recommend lifestyle intervention as a first-line treatment, lifestyle intervention is not widely used in clinic.Inulin can be used as the basic material of f
Placental growth factor promotes neural invasion and predicts disease prognosis in resectable pancreatic cancer
Abstract Background Surgery represents the only curative treatment option for pancreatic ductal adenocarcinoma (PDAC), but recurrence in more than 85% of patients limits the success of curative-intent tumor resection.Neural invasion (NI), particularly the spread of tumor cells along Caster Accessories nerves into extratumoral regions of the pancrea
The invention of writing on Rapa Nui (Easter Island). New radiocarbon dates on the Rongorongo script
Abstract Placing the origin of an undeciphered script in time is crucial to understanding the invention of writing in human Dresser history.Rapa Nui, also known as Easter Island, developed a script, now engraved on fewer than 30 wooden objects, which is still undeciphered.Its origins are also obscure.Central to this issue is whether the script was
SULPHIDE MINERALIZATION IN UPPER WESTPHALIAN COAL SEAMS FROM THE EASTERN PART OF THE UPPER SILESIAN COAL BASIN
Morphologically diversified sulphide mineralization has been found in No.301 and Dinner Forks 302 coal seams (Westphalian B).The main sulphide is pyrite which forms veinlets cross-cutting the sedimentary fabrics of the coal, encrusts the cellular structures and intergrowths with oxysulphides.Two generations of pyrites were observed: the preceding a
A model of cardiovascular disease giving a plausible mechanism for the effect of fractionated low-dose ionizing radiation exposure.
Atherosclerosis is the main cause of coronary heart disease and stroke, the two major causes of death in developed society.There is emerging evidence of excess risk of cardiovascular disease at low radiation doses in various occupationally exposed groups receiving small daily radiation doses.Assuming that they are causal, the mechanisms for effects